The Harrison's Principles of Internal Medicine, 18e, Videos & Animations feature comprehensive demonstrations and tutorials covering essential clinical procedures. (Requires QuickTime)
PART 10:  Disorders of the Cardiovascular System

SECTION 5  Vascular Disease
e33  Atlas of Percutaneous Revascularization (View PDF)

Case 1: Chronic Total Occlusion

Video e33-1  Baseline left coronary angiogram shows an occluded LCx with left-to-left collaterals originating from LAD septal vessels.

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Video e33-2  Attempts to cross the total occlusion in the LCx using a hydrophilic wire and an antegrade approach were not successful, with the wire tracking to the right of the trajectory.
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Video e33-3  The LAD septal collateral is accessed with a guidewire and directed toward the distal LCx to cross the total occlusion retrograde.
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Video e33-4  The total occlusion is crossed retrograde. The wire is snared in the guide, exteriorized, and used to provide antegrade access to the LCx.
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Video e33-5  Antegrade flow in the LCx is restored after balloon inflation.

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Video e33-6  Following stenting of the total occlusion, blood flow in the distal vessel is improved and a second significant stenosis is seen.

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Video e33-7  Final result after LCx stenting.

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Case 2: Birfurcation Stenting

Video e33-8  Baseline angiogram of the left coronary circulation shows the significant stenosis in the mid-LAD and the bifurcation lesion involving a large diagonal branch.
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Video e33-9  Both vessels are accessed with guidewires and pretreated with balloon angioplasty.

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Video e33-10  Result after balloon angioplasty.

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Video e33-11  Stent being positioned in the LAD.

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Video e33-12  LAD post-stent result.

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Video e33-13  Stent deployed in diagonal branch through the stent struts in the LAD using the "culotte" technique.

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Video e33-14  Diagonal branch post-stent result.

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Video e33-15  Simultaneous inflation of two 2.5-mm "kissing" balloons.

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Video e33-16  Final postbifurcation stenting result.

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Case 3: Inferior Myocardial Infarction-Thrombus and Manual Thrombectomy

Video e33-17  The right coronary artery (RCA) is totally occluded with filling defects in the vessel after contrast injection, indicating thrombus is present in the vessel.
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Video e33-18  An angioplasty wire is threaded through the thrombotic lesion, but this does not restore blood flow to the distal vessel.

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Video e33-19  Result after manual thrombectomy and thrombus extraction. The "culprit" ruptured plaque and residual thrombus are now apparent in the vessel.
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Video e33-20  After balloon angioplasty and stenting, thrombus is still present.

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Video e33-21  After repeat manual thrombectomy and expansion of the stent, the thrombus is no longer present.

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Video e33-22  Final Result.

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Case 4: Saphenous Vein Graft Intervention with Distal Protection

Video e33-23  Saphenous vein graft to a first obtuse marginal branch with an 80% eccentric stenosis in the midgraft.

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Video e33-24  A distal protection device is deployed past the lesion.

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Video e33-25  Angioplasty balloon inflation with the distal protection device in place.

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Video e33-26  Final result after stent placement.

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Case 5: Unprotected Left Main PCI in a High-Risk Patient

Video e33-27  Baseline left coronary artery injection in right anterior oblique (RAO) cranial projection shows a high-grade calcified stenosis in the left main coronary artery and a significant stenosis in the proximal LAD.
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Video e33-28  In the left anterior oblique (LAO) caudal view, the left main coronary artery lesion can be seen to extend into the ostia of both the LCx and the LAD.
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Video e33-29  Guide wires were placed into both the LCx and LAD. After the left main coronary artery and LCx are dilated with balloon angioplasty, the proximal LAD is dilated and a long drug-eluting stent is placed to...
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Video e33-30  The bifurcation lesion in the left main coronary artery extending into the LCx and LAD ostia is treated using a "culotte" technique. First, a drug-eluting stent is placed in the left main coronary...
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Video e33-31  Next, the LAD wire is removed and passed through the stent into the distal LAD. A second drug-eluting stent is deployed through the struts of the left main coronary artery/LCx stent.
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Video e33-32  Following rewiring of the LCx, both stents are redilated simultaneously ("kissing" balloons).

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Video e33-33  The final result in the LAO caudal view.

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Video e33-34  The final result in the RAO cranial view showing patent left main, LCx, and LAD coronary arteries.

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Case 6: Multivessel PCI in a Diabetic Patient

Video e33-35  Baseline angiogram of the left coronary circulation in the RAO view shows the total occlusion of the second obtuse marginal branch with delayed retrograde filling via collateral vessels and a high-grade...
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Video e33-36  A guidewire is passed through the total occlusion and the lesion is pretreated with balloon angioplasty.

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Video e33-37  Following placement of a drug-eluting stent in the lesion, the vessel is widely patent. A third obtuse marginal vessel, not previously seen, now fills faintly (TIMI 1 flow) with contrast but was not treated.
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Video e33-38  The ramus intermedius lesion was crossed with a guidewire and pretreated with balloon angioplasty.

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Video e33-39  A drug-eluting stent is placed across the ramus lesion and deployed. The final result shows no residual stenosis in either the ramus or second obtuse marginal vessels.
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Video e33-40  Baseline angiogram of the RCA shows a high-grade lesion in the midsegment of the vessel.

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Video e33-41  The lesion was pretreated with balloon dilation followed by stent deployment.

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Video e33-42  The final result shows no residual stenosis in the mid-RCA.

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Case 7: Very Late Stent Thrombosis of a Proximal Lad Drug-Eluting Stent

Video e33-43  Baseline angiogram showing a total occlusion of the proximal LAD within the drug-eluting stent and a significant stenosis at the origin of the LCx.
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Video e33-44  The LAO view shows the LCx stenosis with a filling defect, indicating that thrombus is present in the vessel lumen.

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Video e33-45  The LAD lesion was crossed with a guidewire, which resulted in slow filling of the mid-LAD (TIMI 2 flow), and revealed thrombus filling the stent.
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Video e33-46  The final result after LAD and LCx stenting. The LAD lesion was pretreated with balloon angioplasty and a bare metal stent was deployed to cover the proximal lesion. The LCx ostial lesion was...
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Case 8: Transcatheter Aortic Valve Transplantation

Video e33-47  Aortogram shows patent coronary arteries and minimal aortic insufficiency.

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Video e33-48  Balloon valvuloplasty is performed with rapid ventricular pacing at 180 bpm.

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Video e33-49  A 26-mm Edwards-SAPIEN valve is positioned using fluoroscopic and transesophageal echo guidance and deployed.

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Video e33-50  Aortogram after valve deployment shows a functional valve with mild aortic insufficiency and without impingement of the coronary ostia.
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Case 9: Atrial Septal Defect Closure

Video e33-51  A sizing balloon is placed across the ASD.

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Video e33-52  An Amplatzer septal occluder is being positioned across the ASD.

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Video e33-53  The two discs of the device in place across the ASD.

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