PART 17: Neurologic Disorders
SECTION 5 Psychiatric Disorders
390 Biology of Psychiatric Disorders
 | Figure 390-1 Neural circuitry of depression and addiction. The figure shows a simplified summary of a series of limbic circuits in brain that regulate mood and motivation and are implicated in depression and addiction. Shown in the figure are the hippocampus (HP) and amygdala (Amy), regions of prefrontal cortex, nucleus accumbens... |
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 | Figure 390-2 Opiate action in the locus coeruleus (LC). Binding of opiate agonists to μ-opioid receptors catalyzes nucleotide exchange on Gi and Go proteins, leading to inhibition of adenylyl cyclase, neuronal hyperpolarization via activation of K+ channels, and inhibition of neurotransmitter release... |
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