PART 16: Endocrinology and Metabolism
SECTION 1 Endocrinology
343 Pheochromocytoma
 | Figure 343-1 The paraganglial system and topographic sites (in red) of pheochromocytomas and paragangliomas. [Parts A,B, from WM Manger, RW Gifford: Clinical and experimental pheochromocytoma. Cambridge, Blackwell Science, 1996; Part C, from GG Glenner, PM Grimley: Tumors of the Extra-adrenal... |
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 | Figure 343-2 Neurofibromatosis. A. MRI of bilateral adrenal pheochromocytoma. B. Cutaneous neurofibromas. C. Lisch nodules of the iris. D. Axillary freckling. (Part A from HPH Neumann et al: Keio J Med 54:15, 2005; with... |
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 | Figure 343-3 Multiple endocrine neoplasia type 2. Multifocal medullary thyroid carcinoma shown by (A) MIBG scintigraphy and (B) operative specimen Arrows demonstrate the tumors; arrowheads show the tissue bridge of the cut specimen. Bilateral adrenal pheochromocytoma shown by ( |
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 | Figure 343-4 Von Hippel-Lindau disease. Retinal angioma (A); hemangioblastomas of cerebellum are shown by MRI in (B) brainstem; (C and D) spinal cord; (E) bilateral pheochromocytomas and bilateral... |
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 | Figure 343-5 Paraganglioma syndrome. PGL1, a patient with incomplete resection of a left carotid body tumor and the SDHD W5X mutation. A. 18F-dopa positron emission tomography demonstrating tumor uptake in the right jugular glomus, the right carotid body, the left carotid body,... |
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 | Figure 343-6 Mutation distribution in the RET, VHL, NF1, SDHB, and SDHD genes. A. Correlation with age. The bars depict the frequency of sporadic or various inherited forms of pheochromocytoma in different age groups. The inherited disorders are much more common among younger individuals presenting with... |
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