PART 15: Disorders of the Joints and Adjacent Tissues
SECTION 2 Disorders of Immune-Mediated Injury
321 Rheumatoid Arthritis
 | Figure 321-1 Metacarpophalangeal and proximal interphalangeal joint swelling in rheumatoid arthritis. (Courtesy of the American College of Rheumatology Image Bank.) |
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 | Figure 321-2 Extraarticular manifestations of rheumatoid arthritis. |
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 | Figure 321-3 Global prevalence rates of rheumatoid arthritis (RA) with genetic associations. Listed are the major genetic alleles associated with RA. While human leukocyte antigen (HLA)-DRB1 mutations are found globally, some alleles have been associated with RA in only certain ethnic groups. |
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 | Figure 321-4 Pathophysiologic mechanisms of inflammation and joint destruction. Genetic predisposition along with environmental factors may trigger the development of rheumatoid arthritis (RA), with subsequent synovial T cell activation. CD4+ T cells become activated by antigenpresenting cells (APCs)... |
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 | Figure 321-5 X-ray demonstrating progression of erosions on the proximal interphalangeal joint. (Courtesy of the American College of Rheumatology.) |
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