PART 14: Disorders of the Gastrointestinal System
SECTION 2 Liver and Biliary Tract Disease
307 Alcoholic Liver Disease
 | Figure 307-1 Biomedical and cellular pathogenesis of liver injury secondary to chronic ethanol ingestion. MAA, malondialdehyde-acetaldehyde; TNF, tumor necrosis factor; TGF, transforming growth factor; IL, interleukin; PPAR, peroxisome proliferator-activated receptor; RXR, retinoid X receptor. |
view large |
 | Figure 307-2 Effect of glucocorticoid therapy of severe alcoholic hepatitis on short-term survival: the result of a meta-analysis of individual data from three studies. Prednisolone, solid line; placebo, dotted line. (Adapted from Mathurin et al., with permission from Elsevier... |
view large |
 | Figure 307-3 Treatment algorithm for alcoholic hepatitis. As identified by a calculated discriminant function >32 (see text), patients with severe alcoholic hepatitis, without the presence of gastrointestinal bleeding or infection, would be candidates for either glucocorticoids or pentoxifylline... |
view large |
