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PART 12: Critical Care Medicine
SECTION 2   Shock and Cardiac Arrest

271 Severe Sepsis and Septic Shock
Robert S. Munford

Figure 271-1  Mortality rates among patients who received tissue factor pathway inhibitor (TFPI) or placebo, shown as the running average over the course of the clinical trial. The drug seemed highly efficacious at the interim analysis in December 2000, but this trend reversed later in the tria ...
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Figure 271-2  Influence of age and prior health status on outcome from severe sepsis. With modern therapy, fewer than 10% of previously healthy young individuals (below 35 years of age) die with severe sepsis; the case-fatality rate then increases slowly through middle and old age. The most com ...
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