PART 10: Disorders of the Cardiovascular System
SECTION 5 Vascular Disease
250 Pulmonary Hypertension
 | Figure 250-1 An algorithm for the workup of a patient with unexplained pulmonary hypertension. All potential etiologies and associated conditions must be investigated in a patient with clinical findings consistent with pulmonary hypertension. COLD, chronic obstructive lung disease; CBC, complete blood count; ANA, antinuclear antibodies; HIV, human immunodeficiency virus; TSH, thyroid-stimulating... |
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 | Figure 250-2 Multiple biologic pathways that can lead to pulmonary arterial hypertension. Some of the better-characterized ones are illustrated. Because of the redundancy in these pathways and the spectrum of abnormalities that may coexist, it is unlikely that a single agent will produce disease reversal. BMPR-2, bone morphogenetic protein receptor-2; HIF, hypoxia inducible factor; KV 1.5,... |
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