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PART 9: Terrorism and Clinical Medicine

222 Chemical Terrorism
Charles G. Hurst / Jonathan Newmark / James A. Romano, Jr.

Figure 222-1  Large bulla formation from mustard burn in a patient. Although the blisters on this patient involved only 7% of the body surface area, this patient still required hospitalization in a burn intensive care unit.
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Figure 222-2  Schematic diagram of pseudomembrane formation as is seen in high-dose sulfur mustard vapor inhalation exposure. In World War I, severe inhalation exposure often caused death via obstruction of large airways.
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Figure 222-3  World War I photograph of troops exposed to sulfur mustard vapor. The vast majority of these troops survived with no long-term damage to the eyes; however, they were effectively rendered blind for days to weeks.
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Figure 222-4  Schematic diagram of the pathophysiology of nerve agent exposure. Nerve agent () binds to the active site of acetylcholinesterase (AChE), which is shown as floating free in space but is in reality a postsynaptic membrane-bound enzyme. As a result, acetylcholine (), which normally is...
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Figure 222-5  Antidotes to nerve agents.A.MARK I autoinjector set containing one 600-mg dose of 2-pralidoxime chloride and one 2-mg dose of atropine. Such sets are carried by all U.S. military forces in a potentially...
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