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PART 8: Infectious Diseases
SECTION 15   Infections Due to RNA Viruses

197 Ebola and Marburg Viruses
Clarence J. Peters

Figure 197-1  Phylogenetic tree of filoviruses. Marburgvirus and Ebolavirus are seen to be two different genera. The genus Ebolavirus includes five distinct species. Note that the Yambuku and Kikwit Zaire viruses are virtually identical even though the...
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Figure 197-2  Left: Geographic sites of Ebolavirus species identification, as represented by dots (yellow, Zaire; green, Sudan; red, Côte d'Ivoire; black, Bundibugyo), in or adjacent to the Central African primary or secondary forest. Even...
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Figure 197-3  Maps of the African continent and the country of Gabon (with adjacent Republic of the Congo) show the geographic distribution of Marburgvirus identification. Red dots indicate a case or an epidemic. Uige, Angola, is the site of the largest Marburg epidemic (252 cases, 90% mortality rate). The Angolan...
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Figure 197-4  Ebola virions: diagnostic specimen from the first passage in Vero cells of a blood sample from a patient. Some of the filamentous (negatively stained) virions were fused together, end-to-end, giving the appearance of a "bowl of spaghetti." This image was from the first isolation and visualization of Ebola virus in 1970.
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