PART 8: Infectious Diseases
SECTION 8 Mycobacterial Diseases
167 Nontuberculous Mycobacterial Infections
 | Figure 167-1 Cytokine interactions of infected macrophages (Mφ) with T and natural killer (NK) lymphocytes. Infection of macrophages by mycobacteria (AFB) leads to the release of heterodimeric interleukin 12 (IL-12). IL-12 acts on its receptor complex, with consequent STAT4 activation and production of homodimeric interferon γ (IFNγ). IFNγ acts... |
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 | Figure 167-2 Chest CT of a patient with pulmonary MAC infection. Arrows indicate the "tree-in-bud" pattern of bronchiolar inflammation (peripheral right lung) and bronchiectasis (central right and left lungs). |
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