< Back to Images

PART 8: Infectious Diseases
SECTION 6   Diseases Caused by Gram-Negative Bacteria

142 Gas Gangrene and Other Clostridial Infections
Amy E. Bryant / Dennis L. Stevens

Figure 142-1  Scanning electron micrograph of C. perfringens.
view large
Figure 142-2  Radiograph of patient with spontaneous gas gangrene due to C. septicum, demonstrating gas in the affected arm and shoulder.
view large
Figure 142-3  Schematic illustration of the molecular mechanisms of C. perfringens α toxin–induced platelet/neutrophil aggregates. Homotypic aggregates of platelets (not shown) and heterotypic aggregates of platelets and leukocytes are due to α toxin-induced activation of the platelet...
view large
Figure 142-4  Histopathology of experimental gas gangrene due to C. perfringens, demonstrating widespread muscle necrosis, a paucity of leukocytes in infected tissues, and accumulation of leukocytes in adjacent vessels (arrows). These features are due to the effects of α and Θ toxins on muscle cells, platelets, leukocytes, and endothelial...
view large