PART 8: Infectious Diseases
SECTION 4 Approach to Therapy for Bacterial Diseases
133 Treatment and Prophylaxis of Bacterial Infections
 | Figure 133-1 Mechanisms of action of and resistance to antibacterial agents. Black lines trace the routes of drug interaction with bacterial cells, from entry to target site. The letters in each figure indicate specific antibacterial agents or classes of agents, as shown in |
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 | Figure 133-2 Relationship between the pharmacokinetic-pharmacodynamic (PK-PD) properties of an antibiotic and susceptibility. An organism is considered “susceptible” to an antibiotic if the drug's minimal inhibitory concentration (MIC) is below its “breakpoint” concentration (see text). PK-PD investigations... |
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