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PART 7: Oncology and Hematology
SECTION 2   Hematopoietic Disorders

105 Megaloblastic Anemias
A. Victor Hoffbrand

Figure 105-1  The role of folates in DNA synthesis and in formation of S-adenosylmethionine (SAM), which is involved in numerous methylation reactions. [Reprinted from AV Hoffbrand et al (eds), Postgraduate Haematology, 5th ed, Oxford, UK, Blackwell Publishing, 2005; with permission.]
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Figure 105-2  A. The peripheral blood in severe megaloblastic anemia. B. The bone marrow in severe megaloblastic anemia. [Reprinted from AV Hoffbrand et al (eds), Postgraduate Haematology, 5th ed, Oxford, UK, Blackwell Publishing, 2005; with...
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