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54 Immunologically Mediated Skin Diseases
Kim B. Yancey / Thomas J. Lawley

	Figure 54-1  Pemphigus vulgaris. A. Pemphigus vulgaris demonstrating flaccid bullae that are easily ruptured, resulting in multiple erosions and crusted plaques. B. Pemphigus vulgaris almost invariably involves the oral mucosa and may...
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	Figure 54-2  Bullous pemphigoid with tense vesicles and bullae on erythematous, urticarial bases. (Courtesy of the Yale Resident's Slide Collection; with permission).
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	Figure 54-3  Dermatomyositis. Periorbital violaceous erythema characterizes the classic heliotrope rash. (Courtesy of James Krell, MD; with permission.)
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	Figure 54-4  Gottron's sign. Dermatomyositis often involves the hands as erythematous flat-topped papules over the knuckles (Gottron's sign). Periungual telangiectases are also evident.
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	Figure 54-5  A. Acute cutaneous lupus erythematosus showing prominent, scaly, malar erythema. Involvement of other sun-exposed sites is also common. B. Acute cutaneous LE on the upper chest demonstrating brightly erythematous and slightly edematous papules and plaques. (B, Courtesy of Robert Swerlick, MD; with...
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	Figure 54-6  Discoid lupus erythematosus. Violaceous, hyperpigmented, atrophic plaques, often with evidence of follicular plugging, which may result in scarring, are characteristic of discoid lupus erythematosus (also called chronic cutaneous lupus erythematosus).
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	Figure 54-7  Scleroderma showing acral sclerosis and focal digitalulcers.
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	Figure 54-8  Scleroderma often eventuates in development of an expressionless, masklike facies.
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