PART 2: Cardinal Manifestations and Presentation of Diseases
SECTION 3 Nervous System Dysfunction
27 Sleep Disorders
 | Figure 27-1 Stages of REM sleep (solid bars), the three stages of NREM sleep, and wakefulness over the course of the entire night for representative young and older adult men. Characteristic features of sleep in older people include reduction of slow-wave sleep, frequent spontaneous awakenings, early sleep onset, and early morning... |
view large |
 | Figure 27-2 Model of the molecular feedback loop at the core of the mammalian circadian clock. The positive element of the feedback loop (+) is the transcriptional activation of the Per1 gene (and probably other clock genes) by a heterodimer of the... |
view large |
 | Figure 27-3 Polysomnographic recordings of (A) obstructive sleep apnea and (B) periodic limb movement of sleep. Note the snoring and reduction in air flow in the presence of continued respiratory effort, associated with the subsequent oxygen desaturation... |
view large |
